SCHEMBL20152999

SCHEMBL20152999

O=C(CCc1cc(O)ccc1F)CCc1cc(O)ccc1F

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.49
ALDH1A1 P00352 1/20 0.45
MAPK1 P28482 1/20 0.45
TYR P14679 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20152924 0.90 CHRNA7 (0.42) CHRNA7ALDH1A1MAPK1
SCHEMBL28038980 0.82 CES2 (0.45) ALDH1A1
SCHEMBL27624283 0.81 FFAR4 (0.41)
SCHEMBL8100867 0.80 TYR (0.68) TYR
SCHEMBL3168506 0.79 CYP4F2 (0.51) CHRNA7ALDH1A1
SCHEMBL15130521 0.78 TAAR1 (0.50) ALDH1A1MAPK1TYR
SCHEMBL20152915 0.77 NPSR1 (0.47)
SCHEMBL20152943 0.77 HSD17B10 (0.45)
SCHEMBL20153030 0.77 CHRNA7 (0.38) CHRNA7TYR
SCHEMBL14770069 0.77 CHRNA7 (0.38) CHRNA7TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018086197-A1 CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE 南方科技大学 2018-05-17 WO disclosed