Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | IAPP | P10997 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28910439 | 0.91 | IAPP (0.50) | NPSR1IAPPCYP3A4TSHRRECQL | |
| SCHEMBL20152975 | 0.90 | NPSR1 (0.40) | NPSR1 | |
| SCHEMBL20152924 | 0.90 | CHRNA7 (0.42) | NPSR1 | |
| SCHEMBL20152931 | 0.87 | TTR (0.44) | — | |
| SCHEMBL20152945 | 0.85 | ESR2 (0.51) | NPSR1 | |
| SCHEMBL27802926 | 0.85 | NPSR1 (0.47) | NPSR1 | |
| SCHEMBL16318981 | 0.81 | CYP4F2 (0.54) | — | |
| SCHEMBL20152934 | 0.81 | TRPV1 (0.41) | NPSR1IAPPCYP3A4TSHR | |
| SCHEMBL27624251 | 0.79 | NPSR1 (0.46) | NPSR1CYP3A4TSHR | |
| SCHEMBL27643697 | 0.79 | NPSR1 (0.46) | NPSR1IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2025-01-14 | — | — | US | disclosed |
| CN-115246765-B | Preparation method and application of spiro diphenol and biphosphinate thereof | 广东欧凯新材料有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115385960-A | Preparation method and application of oxaspiro compound with large steric hindrance | 惠州凯特立斯科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-115304617-A | Synthesis method of oxaspiro diphenol with large steric hindrance and diphosphine ligand thereof | 惠州凯特立斯科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115246765-A | Preparation method and application of spirocyclic diphenol and diphosphonite thereof | 惠州凯特立斯科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| CN-115246767-A | Synthesis method of spiro diphenol with large steric hindrance and diphosphonite compound thereof | 惠州凯特立斯科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | GUANGDONG OXO CHEM LTD. (CN) | 2022-08-04 | — | — | US | disclosed |
| WO-2018086197-A1 | CATALYTIC ASYMMETRIC SYNTHESIS METHOD FOR CHIRAL SPINOL DERIVATE | 南方科技大学 | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | SOST, BPGM, PFKFB3 | NPSR1 219/4885IAPP 4336/4885CYP3A4 1587/4885 |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | SOST, BPGM, PFKFB3 | NPSR1 219/4885IAPP 4336/4885CYP3A4 1587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.