Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.64 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710630 | 0.90 | SLC1A2 (0.55) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL9845978 | 0.90 | SLC1A3 (0.55) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL1389492 | 0.90 | CHRM1 (0.76) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL5592479 | 0.88 | SLC1A3 (0.59) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL2903887 | 0.88 | SLC1A2 (0.53) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL2902181 | 0.88 | SLC1A2 (0.53) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL29027157 | 0.88 | FOLH1 (0.59) | SLC1A3SLC1A2SLC1A1FOLH1CYP1A2 | |
| SCHEMBL584092 | 0.87 | CA2 (0.60) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL18307368 | 0.87 | CA2 (0.60) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 | |
| SCHEMBL12973005 | 0.87 | SLC1A1 (0.57) | SLC1A3SLC1A2SLC1A1CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772231-B | Compounds, its synthetic method and therepic use | GILEAD SCIENCES INC. (US) | 2016-02-03 | — | — | CN | disclosed |
| CN-102952033-A | Novel compound, composing method thereof and therapeutic use therefor | GILEAD SCIENCES INC (US) | 2013-03-06 | — | — | CN | disclosed |
| CN-101243096-B | Antiviral compounds | GILEAD SCIENCES INC | 2013-02-06 | — | — | CN | disclosed |
| CN-102216325-A | Method for purifying human growth hormone polypeptides using affinity resins comprising specific ligands | NOVO NORDISK AS | 2011-10-12 | — | — | CN | disclosed |
| CN-101489564-A | Antiviral phosphinate compounds | GILEAD SCIENCES INC (US) | 2009-07-22 | — | — | CN | disclosed |
| CN-100409844-C | neuraminidase inhibitors | GILEAD SCIENCES INC (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-1347693-A | Novel compounds, their synthesis and therapeutic use | GILEAD SCIENCES INC (US) | 2002-05-08 | — | — | CN | disclosed |
| CN-1272105-A | Compound containing six-membered rings, processes for their preparation, and their use as medicaments | GILEAD SCIENCES INC (US) | 2000-11-01 | — | — | CN | disclosed |
| CN-1238762-A | Piperidine compounds | GILEAD SCIENCES INC (US) | 1999-12-15 | — | — | CN | disclosed |
| US-5434276-A | Process for making N-acyl taurides | FINETEX, INC. (US) | 1995-07-18 | — | — | US | disclosed |
| WO-1995018095-A1 | PROCESS FOR MAKING N-ACYL TAURIDES | FINETEX, INC. (US) | 1995-07-06 | — | — | WO | disclosed |
| US-4352759-A | CRYSTALLIZATION IN ALCOHOL, AMIDATION | CHASE MANHATTAN BANK, THE NATIONAL ASSOCIATION | 1982-10-05 | — | — | US | disclosed |
| US-4233229-A | REACTING ACID CHLORIDE, TAURINE SALT, ALKALI METAL HYDROXIDE; PRECIPITATING ALKALI METAL CHLORIDE | GAF CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |