Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 5/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23462651 | 0.91 | KCNK3 (0.39) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL23558962 | 0.90 | OXTR (0.39) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL6108575 | 0.86 | KCNK3 (0.42) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL6108573 | 0.86 | KCNK3 (0.42) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL20139059 | 0.81 | KCNK3 (0.43) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL20141864 | 0.79 | ITGB1 (0.40) | KCNK3KCNK9KMT2AMEN1OXTR | |
| SCHEMBL20158341 | 0.79 | KCNK3 (0.39) | KCNK3KCNK9MAPTKDM4EOXTR | |
| SCHEMBL6106081 | 0.79 | NNMT (0.43) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL20153392 | 0.79 | NNMT (0.43) | KCNK3KCNK9KMT2AMEN1MAPT | |
| SCHEMBL6219002 | 0.78 | KMT2A (0.40) | KCNK3KCNK9KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089353-A1 | 3-SUBSTITUTED PROPIONIC ACIDS AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |