Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865746 | 1.00 | ACHE (0.44) | ACHEPOLBBLMSIGMAR1MAOB | |
| SCHEMBL17865775 | 1.00 | ACHE (0.44) | ACHEPOLBBLMSIGMAR1MAOB | |
| SCHEMBL17865732 | 0.87 | POLB (0.46) | POLBALDH1A1USP2LMNAKMT2A | |
| SCHEMBL20153496 | 0.87 | POLB (0.46) | POLBALDH1A1USP2LMNAKMT2A | |
| SCHEMBL17865733 | 0.87 | POLB (0.46) | POLBALDH1A1USP2LMNAKMT2A | |
| SCHEMBL19521228 | 0.82 | ADAMTS5 (0.48) | — | |
| SCHEMBL19521230 | 0.82 | ADAMTS5 (0.48) | — | |
| SCHEMBL19521240 | 0.82 | ADAMTS5 (0.48) | — | |
| SCHEMBL19541331 | 0.82 | ADAMTS5 (0.48) | — | |
| SCHEMBL17999632 | 0.81 | PIK3CD (0.35) | ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975879-B2 | Beta lactams as modulators of glutamate uptake and methods for use thereof | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-22 | — | — | US | claimed |