SCHEMBL20153640

SCHEMBL20153640

CCc1cnc(-c2ccc3c(c2)oc2ccccc23)o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.41
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRE P78334 1/20 0.40
GABRA6 Q16445 1/20 0.40
GABRG1 Q8N1C3 1/20 0.40
GABRG3 Q99928 1/20 0.40
GABRQ Q9UN88 1/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16892134 0.81 AHR (0.44) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL16886051 0.79 AHR (0.41) AHRGABRPGABRDGABRA1GABRB1
SCHEMBL16072945 0.77 CYP1A2 (0.49) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL12827256 0.75 CYP11B1 (0.55) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL7913698 0.73 AHR (0.63) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL23627817 0.71 BCL2 (0.45) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL16886054 0.71 LTA4H (0.46) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL15501707 0.70 AHR (0.55) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL18697095 0.70 MMP12 (0.44) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL18933421 0.70 MMP12 (0.47) AHRMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180138428-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138428-A1 METAL-ASSISTED DELAYED FLUORESCENT EMITTERS CONTAINING TRIDENTATE LIGANDS SLC30A6, SLC30A5, BRI3BP AHR 3397/4885GABRP 111/4885GABRD 1581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.