Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201537 | 1.00 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL6731394 | 1.00 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL29284778 | 0.89 | TDP1 (0.43) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL27509183 | 0.85 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL6825269 | 0.84 | TSHR (0.47) | TSHRALDH1A1RAB9A | |
| SCHEMBL58206 | 0.81 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL16594360 | 0.80 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL16594361 | 0.80 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL11798275 | 0.79 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL7717208 | 0.78 | IDO1 (0.46) | TSHRIDO1AGXTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360609-A | VINYLAROMATIC POLYMER, ACTIVE ALLYL OR BENZYL CARBON, ARYLSULFONATE CATALYST | THE DOW CHEMICAL COMPANY (US) | 1982-11-23 | — | — | US | claimed |
| CN-117940438-A | Heterocyclic compounds as MAP4K1 inhibitors | 缆图药品公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115043966-B | Main catalyst and catalyst for preparing ultra-high molecular weight polypropylene, preparation method and application | 上海化工研究院有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115043966-A | Main catalyst and catalyst for preparing ultrahigh molecular weight polypropylene, preparation method and application | 上海化工研究院有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-107285998-B | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone | 江苏剑牌农化股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-107285998-B | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone | 江苏剑牌农化股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| WO-2021070491-A1 | PHOTOCURABLE COMPOSITION FOR NANOIMPRINTING | サンアプロ株式会社 | 2021-04-15 | — | — | WO | disclosed |
| US-10787576-B2 | Method for the preparation of a coating comprising oligomeric alkynes | ÉCOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) EPFL-TTO (CH) | 2020-09-29 | — | — | US | disclosed |
| EP-3599239-A1 | METAL ORGANIC FRAMEWORKS AND METHODS FOR USING THEREOF | Ecole Polytechnique Federale De Lausanne (EPFL) EPFL-TTO (CH) | 2020-01-29 | — | — | EP | disclosed |
| CN-109336952-A | Novel nuclear magnetic contrast lipid capable of being released under light control and preparation method thereof | 大连理工大学 | 2019-02-15 | — | — | CN | disclosed |
| CN-86105877-A | 6-methyl-3,4-dihydro-1,2,3-oxygen thiazine-4-ketone 2, the preparation of 2-dioxide and purification process thereof | — | 1987-03-04 | — | — | CN | disclosed |
| US-4638063-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-20 | — | — | US | disclosed |
| CN-85104278-A | A kind of preparation 6-methyl-3,4-dihydro-1,2,3-thiazine-4-ketone 2, the method for 2-dioxide and nontoxicity salt thereof | — | 1986-12-03 | — | — | CN | disclosed |
| CN-85104277-A | Process for preparing 6-methyl-3, 4-dihydro-1, 2, 3-thiazin-4-one 2, 2-dioxide and its non-toxic salts, and process for preparing acetoacetamide-N-sulfonic acid | — | 1986-12-03 | — | — | CN | disclosed |
| US-4625024-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-25 | — | — | US | disclosed |
| US-4607100-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-08-19 | — | — | US | disclosed |
| EP-0173082-A1 | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-05 | — | — | EP | disclosed |
| US-4563521-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
| EP-0159516-A1 | Method for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-10-30 | — | — | EP | disclosed |
| EP-0155634-A2 | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and of its non-toxic salts, as well as of acetoacetamide-N-sulfonic acid occurring as an intermediary in this process, and its salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-09-25 | — | — | EP | disclosed |