Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201537 | 1.00 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL201538 | 1.00 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL29284778 | 0.89 | TDP1 (0.43) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL27509183 | 0.85 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL6825269 | 0.84 | TSHR (0.47) | TSHRALDH1A1RAB9A | |
| SCHEMBL58206 | 0.81 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL16594360 | 0.80 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL16594361 | 0.80 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL11798275 | 0.79 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1L3MBTL1 | |
| SCHEMBL7717208 | 0.78 | IDO1 (0.46) | TSHRIDO1AGXTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020072695-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2020-04-09 | — | — | WO | disclosed |
| US-20200108075-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2020-04-09 | — | — | US | disclosed |
| US-6682869-B2 | IN POLYMER | SHIN-ETU CHEMICAL CO., LTD. (JP) | 2004-01-27 | — | — | US | disclosed |
| CN-1400208-A | Method for preparing 6-methyl-1,2,3-oxazine-4(3H)-ketone-2,2-dioxopotassium salt | DING HONGHUI (CN) | 2003-03-05 | — | — | CN | disclosed |
| US-20020037534-A1 | Combinatorial preparation of a substance library with removal of a zwitterionic compound by precipitation | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-28 | — | — | US | disclosed |
| US-20010038971-A1 | Chemical amplification, positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-11-08 | — | — | US | disclosed |
| EP-0704762-B1 | Resist material and pattern formation | WAKO PURE CHEM IND LTD (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5558971-A | HYDROXYSTYRENE POLYMER DERIVATIVES, PHOTOACID GENERATOR | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5558976-A | HYDROXYSTYRENE POLYMER DERIVATIVES, PHOTOACID GENERATOR, PHOTORESISTS | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0704762-A1 | Resist material and pattern formation | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| US-4695629-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| CN-86105506-A | 6-methyl-3,4-dihydro-1,2,3-dislikes thiazine-4-ketone 2, the preparation method of 2-dioxide | — | 1987-04-29 | — | — | CN | disclosed |
| CN-86105339-A | 6-methyl-3,4-dihydro-1,2,3-oxygen thia azine hexamethylene-4-ketone 2, the preparation of 2-dioxide and method of purification | — | 1987-04-08 | — | — | CN | disclosed |
| CN-86105877-A | 6-methyl-3,4-dihydro-1,2,3-oxygen thiazine-4-ketone 2, the preparation of 2-dioxide and purification process thereof | — | 1987-03-04 | — | — | CN | disclosed |
| US-4638063-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-20 | — | — | US | disclosed |
| CN-85104277-A | Process for preparing 6-methyl-3, 4-dihydro-1, 2, 3-thiazin-4-one 2, 2-dioxide and its non-toxic salts, and process for preparing acetoacetamide-N-sulfonic acid | — | 1986-12-03 | — | — | CN | disclosed |
| CN-85104278-A | A kind of preparation 6-methyl-3,4-dihydro-1,2,3-thiazine-4-ketone 2, the method for 2-dioxide and nontoxicity salt thereof | — | 1986-12-03 | — | — | CN | disclosed |
| US-4625024-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-11-25 | — | — | US | disclosed |
| US-4607100-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-08-19 | — | — | US | disclosed |
| US-4563521-A | Process for the preparation of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one 2,2-dioxide and its non-toxic salts | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037534-A1 | Combinatorial preparation of a substance library with removal of a zwitterionic compound by precipitation | NEFM, PSPH, NGLY1 | TSHR 3420/4885IDO1 3207/4885AGXT 2815/4885 |
| US-20200108075-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | PHKG1, MAP4K5, HIPK1 | TSHR 4838/4885IDO1 1237/4885AGXT 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.