Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813951 | 0.83 | LTA4H (0.52) | TSHR | |
| SCHEMBL201538 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL201537 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL6731394 | 0.81 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL666545 | 0.79 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL27509183 | 0.79 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL6873209 | 0.77 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL450596 | 0.76 | CA1 (0.44) | IDO1ALDH1A1TDP1CA1CA2 | |
| SCHEMBL114175 | 0.76 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL444754 | 0.76 | LOXL2 (0.41) | ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2558 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324729-A | Synthesis method of 3-alkenyl benzofuran compound | 青岛科技大学 | 2024-07-12 | — | — | CN | claimed |
| CN-113382988-B | Microbiocidal 2-acylamino-thiazole-4-carboxamide derivatives | 先正达农作物保护股份公司 | 2024-06-18 | — | — | CN | claimed |
| CN-117624029-A | Arylpyridine or arylpiperidine derivative or salt thereof, synthesis and application and medicine | 赣江中药创新中心 | 2024-03-01 | — | — | CN | claimed |
| US-20230398529-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2023-12-14 | — | — | US | claimed |
| CN-117164492-A | Organic semiconductor g-C 3 N 4 Method for catalytic synthesis of (E) -vinyl selenone compound | 化学与精细化工广东省实验室 | 2023-12-05 | — | — | CN | claimed |
| EP-4263541-A1 | NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2023-10-25 | — | — | EP | claimed |
| US-20230322776-A1 | NEW ARYL-PYRIDO-PYRIMIDIN-ONE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-10-12 | — | — | US | claimed |
| CN-116710451-A | Novel aryl-pyrido-pyrimidin-one derivatives | 豪夫迈·罗氏有限公司 | 2023-09-05 | — | — | CN | claimed |
| WO-2023164238-A1 | PROTEASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2023-08-31 | — | — | WO | claimed |
| EP-4229040-A1 | ASYMMETRIC TRANSFER HYDROGENATION OF 2-ARYL SUBSTITUTED BICYCLIC PYRIDINE KETONES IN PRESENCE OF A CHIRAL RUTHENIUM CATALYST | Bayer Aktiengesellschaft (DE) | 2023-08-23 | — | — | EP | claimed |
| EP-0126974-A1 | Carboxyalkyl peptide derivatives | G.D. Searle & Co. (US) | 1984-12-05 | — | — | EP | claimed |
| EP-0122482-A1 | Monoazo dyestuffs for polyester fibers | RESEARCH ASSOCIATION OF SYNTHETIC DYESTUFFS (JP) | 1984-10-24 | — | — | EP | claimed |
| EP-0121875-A2 | Process for producing alkaline dischargeable dyeings and prints | BASF Aktiengesellschaft (DE) | 1984-10-17 | — | — | EP | claimed |
| EP-0110073-A1 | Process for the preparation of tetrahydropyridines | BAYER AG (DE) | 1984-06-13 | — | — | EP | claimed |
| EP-0093010-A2 | Alpha-hydroxyethylphosphinates, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-02 | — | — | EP | claimed |
| US-4341700-A | Monoazo compounds having a substituted 1,2,3-triazolyl-5 diazo component radical and an unsubstituted or substituted 1,4-phenylene coupling component radical | SANDOZ LTD. (CH) | 1982-07-27 | — | — | US | claimed |
| US-4178387-A | ADMINISTERING AMIDINOUREAS | WILLIAM H. RORER, INC. (US) | 1979-12-11 | — | — | US | claimed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | claimed |
| US-4015012-A | ANTHELMINTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | claimed |
| US-3970699-A | 4-Acylaminophenylacetamidines and a method for their preparation | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | claimed |