Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.52 |
| ▸ | ITGAV | P06756 | 20/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139307 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGB5 | |
| SCHEMBL20139511 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGB5 | |
| SCHEMBL29744158 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGB5 | |
| SCHEMBL20139303 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGB5 | |
| SCHEMBL29744049 | 0.89 | ITGB3 (0.65) | ITGB3ITGAVITGB5 | |
| SCHEMBL22600391 | 0.87 | ITGB3 (0.56) | ITGB3ITGAVITGB5 | |
| SCHEMBL23677922 | 0.86 | ITGB3 (0.56) | ITGB3ITGAVITGB5 | |
| SCHEMBL22600445 | 0.84 | ITGB3 (0.54) | ITGB3ITGAVITGB5 | |
| SCHEMBL20139246 | 0.82 | ITGB3 (0.67) | ITGB3ITGAVITGB5 | |
| SCHEMBL20139528 | 0.82 | ITGB3 (0.67) | ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089357-A1 | INDAZOLE DERIVATIVES AS αV INTEGRIN ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |