Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.54 |
| ▸ | ITGAV | P06756 | 20/20 | 0.54 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139310 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL20141387 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL29744128 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL29744175 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL20139326 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL29744244 | 0.90 | ITGB3 (0.66) | ITGB3ITGAVITGB5 | |
| SCHEMBL23677855 | 0.89 | ITGB3 (0.54) | ITGB3ITGAVITGB5 | |
| SCHEMBL20153809 | 0.84 | ITGB3 (0.52) | ITGB3ITGAVITGB5 | |
| SCHEMBL23677922 | 0.83 | ITGB3 (0.56) | ITGB3ITGAVITGB5 | |
| SCHEMBL22600391 | 0.82 | ITGB3 (0.56) | ITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028071-B2 | Indazole derivatives as alpha v integrin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-06-08 | — | — | US | disclosed |
| US-20200339540-A1 | INDAZOLE DERIVATIVES AS ALPHA V INTEGRIN ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339540-A1 | INDAZOLE DERIVATIVES AS ALPHA V INTEGRIN ANTAGONISTS | ITGAV, ITGB1, ITGB3 | ITGB3 3/4885ITGAV 1/4885ITGB5 4/4885 |
| US-11028071-B2 | Indazole derivatives as alpha v integrin antagonists | ITGAV, ITGB1, ITGB3 | ITGB3 3/4885ITGAV 1/4885ITGB5 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.