SCHEMBL20154064

SCHEMBL20154064

Cc1ccc(C)n1C(C)(C)CC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.37
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21303923 0.75 SHBG (0.33) SHBG
SCHEMBL19222033 0.73 ESR1 (0.35) ESR1
SCHEMBL20154076 0.69
SCHEMBL19901140 0.69 GPR3 (0.43) ALDH1A1POLB
SCHEMBL23772631 0.65 KDM4E (0.31) ALDH1A1
SCHEMBL16720058 0.65 MEN1 (0.34) ALDH1A1ESR1
SCHEMBL20125692 0.63 KDM4E (0.35) ALDH1A1POLB
SCHEMBL11512038 0.63
SCHEMBL21719794 0.60
SCHEMBL21721070 0.60 KMT2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790926-B1 PROCESS FOR COATING FIBERS CONTAINING POLAR MOIETIES MILANO POLITECNICO (IT) 2022-06-29 EP disclosed
EP-3755687-B1 ADDUCT BETWEEN A PYRROLIC COMPOUND AND AN INORGANIC OXIDE HYDROXIDE, A SUPER-ADDUCT BETWEEN A PYRROLIC COMPOUND, AN INORGANIC OXIDE HYDROXIDE AND A CARBON ALLOTROPE, ELASTOMERIC COMPOSITION COMPRISING THE SUPER-ADDUCT AND METHODS FOR PRODUCING THE SAME PIRELLI (IT) 2022-06-29 EP disclosed
EP-3538481-B1 ADDUCTS OF PYRROLE DERIVATIVES TO CARBON ALLOTROPES PIRELLI (IT) 2021-08-18 EP disclosed
EP-3538511-B1 ADDUCTS FORMED FROM PRIMARY AMINES, DICARBONYL DERIVATIVES, INORGANIC OXIDE HYDROXYDES AND SP2-HYBRIDIZED CARBON ALLOTROPES PIRELLI (IT) 2021-04-21 EP disclosed
WO-2019215170-A1 PROCESS FOR COATING FIBERS CONTAINING POLAR MOIETIES POLITECNICO DI MILANO (IT) 2019-11-14 WO disclosed
WO-2019162873-A1 ADDUCT BETWEEN A PYRROLIC COMPOUND AND AN INORGANIC OXIDE HYDROXIDE, A SUPER-ADDUCT BETWEEN A PYRROLIC COMPOUND, AN INORGANIC OXIDE HYDROXIDE AND A CARBON ALLOTROPE, ELASTOMERIC COMPOSITION COMPRISING THE SUPER-ADDUCT AND METHODS FOR PRODUCING THE SAME PIRELLI TYRE S.P.A. (IT) 2019-08-29 WO disclosed
WO-2018087688-A1 ADDUCTS FORMED FROM PRIMARY AMINES, DICARBONYL DERIVATIVES, INORGANIC OXIDE HYDROXYDES AND SP2-HYBRIDIZED CARBON ALLOTROPES PIRELLI TYRE S.P.A. (IT) 2018-05-17 WO disclosed
WO-2018087685-A1 ADDUCTS OF PYRROLE DERIVATIVES TO CARBON ALLOTROPES PIRELLI TYRE S.P.A. (IT) 2018-05-17 WO disclosed