Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154222 | 0.87 | RAB9A (0.55) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL20154271 | 0.80 | RAB9A (0.59) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL18924216 | 0.79 | TSHR (0.56) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL22005553 | 0.77 | RAB9A (0.53) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL21550516 | 0.77 | RAB9A (0.71) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL20154269 | 0.77 | RAB9A (0.53) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL20154220 | 0.77 | RAB9A (0.50) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL21572853 | 0.76 | TDP1 (0.58) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL19928470 | 0.74 | TDP1 (0.54) | RAB9ATSHRSMN1; SMN2TDP1KMT2A | |
| SCHEMBL20711150 | 0.73 | RAB9A (0.53) | RAB9ATSHRSMN1; SMN2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538512-B1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2021-06-16 | — | — | EP | disclosed |
| WO-2021018839-A1 | ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2021-02-04 | — | — | WO | disclosed |
| WO-2019002132-A1 | NEW AZAQUINOLINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |
| WO-2018087036-A1 | NEW ANTHELMINTIC QUINOLINE-3-CARBOXAMIDE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2018-05-17 | — | — | WO | disclosed |