Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23575586 | 0.85 | BRD4 (0.34) | BRD4GAAL3MBTL1BRD9BRD7 | |
| SCHEMBL22729417 | 0.78 | BRD4 (0.44) | BRD4GAAL3MBTL1BRD9BRD7 | |
| SCHEMBL15519363 | 0.77 | GAA (0.37) | BRD4GAABRD9CRBN | |
| SCHEMBL16651641 | 0.72 | BRD4 (0.58) | BRD4L3MBTL1BRD9BRD7 | |
| SCHEMBL29613217 | 0.72 | BRD4 (0.58) | BRD4L3MBTL1BRD9BRD7 | |
| SCHEMBL20155010 | 0.71 | DGAT1 (0.40) | — | |
| SCHEMBL17879710 | 0.71 | BRD4 (0.41) | BRD4GAAL3MBTL1BRD9BRD7 | |
| SCHEMBL17963571 | 0.70 | CCNT1 (0.33) | BRD4L3MBTL1 | |
| SCHEMBL28520363 | 0.70 | HTT (0.38) | BRD4L3MBTL1BRD9 | |
| SCHEMBL19657265 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |