Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15069386 | 0.90 | DGAT1 (0.40) | DGAT1NPC1DUTEGFRIGF1R | |
| SCHEMBL1076270 | 0.81 | DGAT1 (0.39) | DGAT1NPC1DUT | |
| SCHEMBL30207672 | 0.78 | NPC1 (0.35) | DGAT1NPC1DUTEGFRIGF1R | |
| SCHEMBL30902997 | 0.77 | DUT (0.35) | DGAT1NPC1DUTEGFRIGF1R | |
| SCHEMBL27214896 | 0.76 | DGAT1 (0.36) | DGAT1NPC1 | |
| SCHEMBL27233836 | 0.76 | NPC1 (0.42) | DGAT1NPC1DUTEGFRIGF1R | |
| SCHEMBL30851323 | 0.76 | NPC1 (0.42) | DGAT1NPC1DUTEGFRIGF1R | |
| SCHEMBL25287397 | 0.75 | DGAT1 (0.38) | DGAT1NPC1DUTEGFRIGF1R | |
| SCHEMBL20155011 | 0.75 | DGAT1 (0.40) | DGAT1NPC1 | |
| SCHEMBL21224611 | 0.75 | DGAT1 (0.40) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |