Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154960 | 0.82 | KDM4C (0.35) | KDM4CNPC1RAB9A | |
| SCHEMBL20154953 | 0.81 | NPC1 (0.38) | KDM4CNPC1RAB9A | |
| SCHEMBL20154951 | 0.79 | NPC1 (0.36) | NPC1 | |
| SCHEMBL20154958 | 0.79 | NPC1 (0.39) | NPC1 | |
| SCHEMBL20155261 | 0.77 | SMN1; SMN2 (0.35) | NPC1BRD4 | |
| SCHEMBL20154976 | 0.77 | BRD4 (0.39) | BRD4 | |
| SCHEMBL20154962 | 0.76 | NPC1 (0.33) | NPC1 | |
| SCHEMBL20155678 | 0.75 | CHKA (0.33) | NPC1 | |
| SCHEMBL20154975 | 0.73 | BRD4 (0.51) | BRD4EP300 | |
| SCHEMBL20155035 | 0.72 | NPC1 (0.36) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |