Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20154953 | 0.89 | NPC1 (0.38) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL20154955 | 0.82 | KDM4C (0.32) | KDM4CNPC1RAB9A | |
| SCHEMBL20155252 | 0.75 | DGAT1 (0.35) | NPC1 | |
| SCHEMBL31703071 | 0.67 | L3MBTL1 (0.34) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL20155011 | 0.66 | DGAT1 (0.40) | NPC1 | |
| SCHEMBL21685157 | 0.65 | KDM4C (0.34) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL21685448 | 0.65 | KDM4C (0.34) | KDM4CNPC1RAB9AL3MBTL1 | |
| SCHEMBL30903015 | 0.64 | DGAT1 (0.33) | NPC1 | |
| SCHEMBL28578047 | 0.63 | KDM4C (0.35) | KDM4CNPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL25229073 | 0.63 | KDM4C (0.47) | KDM4CNPC1RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |