Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155507 | 0.69 | BRD4 (0.39) | BRD4PTGER4 | |
| SCHEMBL20155096 | 0.66 | BRD4 (0.49) | BRD4 | |
| SCHEMBL20155510 | 0.64 | BRD4 (0.47) | BRD4 | |
| SCHEMBL27270334 | 0.62 | PTGER4 (0.55) | PTGER4CRHR1 | |
| SCHEMBL30288293 | 0.58 | USP30 (0.44) | BRD4USP30IRAK4TTK | |
| SCHEMBL11935117 | 0.57 | PTGER4 (0.44) | BRD4PTGER4 | |
| SCHEMBL13438679 | 0.57 | PTGER4 (0.44) | BRD4PTGER4 | |
| SCHEMBL23610920 | 0.57 | BCL6 (0.49) | BRD4PTGER4 | |
| SCHEMBL20155486 | 0.55 | ACHE (0.41) | BRD4PTGER4 | |
| SCHEMBL30288239 | 0.55 | USP30 (0.39) | BRD4USP30IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |