Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.31 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155445 | 0.90 | BRD4 (0.39) | BRD4 | |
| SCHEMBL20155383 | 0.88 | BRD4 (0.35) | BRD4 | |
| SCHEMBL20155530 | 0.88 | BRD4 (0.37) | BRD4 | |
| SCHEMBL20155693 | 0.84 | BRD4 (0.36) | BRD4SCN9A | |
| SCHEMBL20155372 | 0.83 | BRD4 (0.39) | BRD4 | |
| SCHEMBL20155340 | 0.83 | BRD4 (0.40) | BRD4 | |
| SCHEMBL20155715 | 0.82 | BRD4 (0.39) | BRD4 | |
| SCHEMBL20155690 | 0.81 | BRD4 (0.38) | BRD4 | |
| SCHEMBL20155473 | 0.81 | BRD4 (0.39) | BRD4 | |
| SCHEMBL20155073 | 0.81 | BRD4 (0.38) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |