Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155429 | 0.84 | DGAT1 (0.34) | DGAT1NPC1MAPT | |
| SCHEMBL20155011 | 0.77 | DGAT1 (0.40) | DGAT1NPC1MAPT | |
| SCHEMBL20154960 | 0.75 | KDM4C (0.35) | NPC1 | |
| SCHEMBL25608477 | 0.73 | NPC1 (0.35) | DGAT1NPC1 | |
| SCHEMBL29785082 | 0.73 | NPC1 (0.35) | DGAT1NPC1 | |
| SCHEMBL16337618 | 0.73 | NPC1 (0.39) | DGAT1NPC1HTTMAPT | |
| SCHEMBL16382757 | 0.73 | NPC1 (0.39) | DGAT1NPC1HTTMAPT | |
| SCHEMBL20437123 | 0.72 | NPC1 (0.37) | DGAT1NPC1HTTMAPT | |
| SCHEMBL16337272 | 0.72 | NPC1 (0.44) | DGAT1NPC1MAPT | |
| SCHEMBL16336628 | 0.71 | NPC1 (0.37) | DGAT1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |