Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155425 | 0.80 | SOS1 (0.46) | SOS1IDO1THRBCYP2D6CYP2C19 | |
| SCHEMBL20155614 | 0.77 | IDO1 (0.40) | SOS1IDO1THRBALDH1A1GAA | |
| SCHEMBL20155588 | 0.71 | ALDH1A1 (0.37) | SOS1CYP2D6CYP2C19ALDH1A1GAA | |
| SCHEMBL17492772 | 0.71 | SOS1 (0.48) | SOS1THRBALDH1A1GAANPC1 | |
| SCHEMBL28924001 | 0.70 | SOS1 (0.63) | SOS1CYP2D6CYP2C19ALDH1A1GAA | |
| SCHEMBL3607221 | 0.70 | ALDH1A1 (0.44) | SOS1CYP2D6CYP2C19ALDH1A1GAA | |
| SCHEMBL15638643 | 0.69 | ALDH1A1 (0.47) | SOS1IDO1THRBCYP2D6CYP2C19 | |
| SCHEMBL20155496 | 0.69 | SOS1 (0.42) | SOS1IDO1THRBCYP2D6CYP2C19 | |
| SCHEMBL1662774 | 0.68 | MAPK14 (0.41) | SOS1CYP2D6CYP2C19ALDH1A1GAA | |
| SCHEMBL16396266 | 0.68 | SOS1 (0.48) | SOS1CYP2D6CYP2C19ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |