Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155758 | 0.86 | BRD4 (0.46) | BRD4 | |
| SCHEMBL20155168 | 0.85 | BRD4 (0.40) | BRD4 | |
| SCHEMBL20155185 | 0.84 | BRD4 (0.42) | BRD4MAPK1 | |
| SCHEMBL20155652 | 0.83 | BRD4 (0.48) | BRD4 | |
| SCHEMBL20155593 | 0.82 | BRD4 (0.47) | BRD4 | |
| SCHEMBL20155103 | 0.81 | BRD4 (0.42) | BRD4 | |
| SCHEMBL20155625 | 0.81 | BRD4 (0.46) | BRD4 | |
| SCHEMBL20155113 | 0.80 | BRD4 (0.48) | BRD4 | |
| SCHEMBL20155184 | 0.80 | BRD4 (0.40) | BRD4BRAF | |
| SCHEMBL20155764 | 0.79 | BRD4 (0.49) | BRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |