Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155427 | 0.91 | BRD4 (0.48) | BRD4 | |
| SCHEMBL20155737 | 0.87 | BRD4 (0.47) | BRD4MAT2A | |
| SCHEMBL20155619 | 0.86 | BRD4 (0.46) | BRD4 | |
| SCHEMBL20155627 | 0.84 | BRD4 (0.41) | BRD4 | |
| SCHEMBL20155758 | 0.84 | BRD4 (0.46) | BRD4 | |
| SCHEMBL20155756 | 0.84 | BRD4 (0.41) | BRD4MAPK1 | |
| SCHEMBL20155651 | 0.83 | BRD4 (0.43) | BRD4POLBTP53 | |
| SCHEMBL20155006 | 0.83 | BRD4 (0.46) | BRD4 | |
| SCHEMBL20155644 | 0.80 | BRD4 (0.45) | BRD4POLBTP53 | |
| SCHEMBL20155116 | 0.80 | BRD4 (0.45) | BRD4MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086604-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |