⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155299 | 0.62 | — | — | |
| SCHEMBL20194007 | 0.59 | CRHBP (0.39) | — | |
| SCHEMBL20155825 | 0.55 | — | — | |
| SCHEMBL20155840 | 0.55 | — | — | |
| SCHEMBL20155752 | 0.55 | — | — | |
| SCHEMBL22260668 | 0.53 | CRHBP (0.39) | — | |
| SCHEMBL20193985 | 0.52 | — | — | |
| SCHEMBL21341817 | 0.52 | — | — | |
| SCHEMBL20155829 | 0.52 | HTT (0.41) | — | |
| SCHEMBL20194051 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981930-B1 | MAGL inhibitors | ABIDE THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20180134675-A1 | MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2018-05-17 | — | — | US | disclosed |