Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22260668 | 0.81 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL16941945 | 0.77 | CRHBP (0.37) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL10166270 | 0.73 | CRHBP (0.42) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL9924089 | 0.71 | CRHBP (0.41) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL13923529 | 0.71 | CRHBP (0.41) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL16941947 | 0.69 | CRHBP (0.36) | CRHBPCRHR2 | |
| SCHEMBL18363105 | 0.69 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL18745708 | 0.69 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL680047 | 0.69 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL12445299 | 0.69 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981930-B1 | MAGL inhibitors | ABIDE THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |