Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116289 | 0.78 | — | — | |
| SCHEMBL23115588 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTL3MBTL1COMTRECQL | |
| SCHEMBL23115758 | 0.76 | NPC1 (0.46) | SMN1; SMN2ALDH1A1RAB9AGAANPC1 | |
| SCHEMBL18380176 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTL3MBTL1COMTRECQL | |
| SCHEMBL21721687 | 0.75 | SMN1; SMN2 (0.35) | SMN1; SMN2HTTRECQLTSHRRAB9A | |
| SCHEMBL23115605 | 0.72 | BRD4 (0.49) | SMN1; SMN2HTTL3MBTL1GAAMAPT | |
| SCHEMBL22912546 | 0.72 | L3MBTL1 (0.51) | SMN1; SMN2HTTL3MBTL1COMTRECQL | |
| SCHEMBL26357447 | 0.71 | — | — | |
| SCHEMBL24937145 | 0.71 | SMN1; SMN2 (0.37) | SMN1; SMN2HTTL3MBTL1COMTRECQL | |
| SCHEMBL1361978 | 0.70 | L3MBTL1 (0.62) | SMN1; SMN2HTTL3MBTL1COMTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |