Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402261 | 0.78 | HIF1A (0.42) | BACE1HPGDALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL14495383 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPK1MEN1KMT2APTGS1 | |
| SCHEMBL23403250 | 0.73 | HTR2A (0.40) | BACE1HPGDBCL2L1ALDH1A1HSD17B10 | |
| SCHEMBL23400670 | 0.73 | PTGIR (0.42) | HPGDALDH1A1MAPK1POLBATM | |
| SCHEMBL23399704 | 0.73 | HTR2A (0.40) | BACE1HPGDALDH1A1SMN1; SMN2GAA | |
| SCHEMBL472924 | 0.71 | MAPK1 (0.45) | GABRA1GABRB2BACE1BCL2L1MAPK1 | |
| SCHEMBL23399927 | 0.71 | PTGIR (0.47) | ALDH1A1MAPK1POLBMEN1KMT2A | |
| SCHEMBL23403184 | 0.70 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23399782 | 0.70 | PTGS2 (0.52) | ALDH1A1KMT2AMAPTPTGS1PTGS2 | |
| SCHEMBL23400063 | 0.70 | S1PR1 (0.46) | ALDH1A1MAPK1SMN1; SMN2MAPTPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |