Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.55 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3728727 | 0.86 | FDPS (0.58) | FDPSMAOBNFE2L2ALDH1A1KDM4E | |
| SCHEMBL3678457 | 0.83 | FDPS (0.70) | TUBB1FDPSMAOB | |
| SCHEMBL30594189 | 0.83 | FDPS (0.70) | TUBB1FDPSMAOB | |
| SCHEMBL3678458 | 0.83 | FDPS (0.70) | TUBB1FDPSMAOB | |
| Hydrochloric Acid SCHEMBL4715727 | 0.76 | TRPA1 (0.49) | MAOBNFE2L2TNFRSF1AMAPT | |
| SCHEMBL24164775 | 0.75 | TUBB1 (0.66) | TUBB1FDPSNFE2L2ALDH1A1MCL1 | |
| SCHEMBL29090925 | 0.75 | TUBB1 (0.66) | TUBB1FDPSNFE2L2ALDH1A1MCL1 | |
| SCHEMBL584262 | 0.75 | KDM4E (0.73) | TUBB1NFE2L2ALDH1A1MCL1KDM4E | |
| SCHEMBL30548412 | 0.75 | TUBB1 (0.66) | TUBB1FDPSNFE2L2ALDH1A1MCL1 | |
| SCHEMBL584263 | 0.75 | KDM4E (0.73) | TUBB1NFE2L2ALDH1A1MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |