SCHEMBL20156239

SCHEMBL20156239

COC(=O)/C(=C/N)NCCC1(C)OCCO1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20156305 0.83
SCHEMBL20156237 0.71
SCHEMBL16181341 0.70 TSHR (0.45) KMT2A
SCHEMBL20156072 0.69
SCHEMBL20156238 0.68
SCHEMBL16181353 0.67 CASP2 (0.46) KMT2A
SCHEMBL7847493 0.65 TSHR (0.46) KMT2A
SCHEMBL20156293 0.64 KMT2A (0.30) KMT2A
SCHEMBL14445055 0.64 TSHR (0.38) KMT2A
SCHEMBL16181339 0.64 TSHR (0.45) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089358-A1 AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2018-05-17 WO disclosed