Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156326 | 0.75 | ALDH1A1 (0.42) | KMT2A | |
| SCHEMBL20156005 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL20156241 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL16181353 | 0.66 | CASP2 (0.46) | KMT2A | |
| SCHEMBL20156038 | 0.66 | ALDH1A1 (0.36) | — | |
| SCHEMBL11608944 | 0.66 | FAAH (0.45) | KMT2A | |
| SCHEMBL135497 | 0.66 | LMNA (0.44) | KMT2A | |
| SCHEMBL20156072 | 0.65 | — | — | |
| SCHEMBL20156305 | 0.65 | — | — | |
| SCHEMBL20156239 | 0.64 | KMT2A (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |