Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 16/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156351 | 0.88 | MPO (0.35) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL20156071 | 0.88 | MPO (0.35) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL20156073 | 0.85 | FGFR4 (0.34) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL20158352 | 0.82 | MPO (0.39) | MPOFGFR4NPC1RAB9A | |
| SCHEMBL29416391 | 0.80 | MPO (0.38) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL20158202 | 0.80 | MPO (0.38) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL27406314 | 0.80 | MPO (0.40) | MPOFGFR4NPC1RAB9A | |
| SCHEMBL31076000 | 0.80 | MPO (0.37) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL20025188 | 0.80 | MPO (0.37) | MPOFGFR4GPR119NPC1RAB9A | |
| SCHEMBL14380644 | 0.79 | MPO (0.38) | MPOFGFR4GPR119NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |
| WO-2018089358-A1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-17 | — | — | WO | disclosed |