Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | PPARD | Q03181 | 2/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.63 |
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804482 | 0.95 | PPARG (0.58) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10687622 | 0.90 | CYSLTR2 (0.78) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL2009962 | 0.89 | PPARG (0.50) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10686535 | 0.89 | CYSLTR2 (0.79) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10691143 | 0.88 | CYSLTR2 (0.79) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10684785 | 0.88 | CYSLTR2 (0.79) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10687531 | 0.88 | CYSLTR2 (0.79) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10685393 | 0.88 | PPARG (0.78) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL10956728 | 0.88 | PPARG (0.64) | PPARGPPARDPPARACYSLTR2CYSLTR1 | |
| SCHEMBL9498784 | 0.87 | CYSLTR2 (0.58) | PPARGPPARDPPARACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964628-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-06-21 | — | — | US | disclosed |
| US-20100256161-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-10-07 | — | — | US | disclosed |
| US-7759387-B2 | Fibrinogen receptor antagonists and their use | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-07-20 | — | — | US | disclosed |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2007-01-25 | — | — | US | disclosed |
| US-4782176-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1988-11-01 | — | — | US | disclosed |
| US-4672066-A | TREATMENT OF ALLERGIC CONDITIONS AND CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1987-06-09 | — | — | US | disclosed |
| US-4628115-A | LEUKOTRIENE ANTAGONISTS | HOFFMANN-LA ROCHE INC. (US) | 1986-12-09 | — | — | US | disclosed |
| US-4507498-A | Phenoxycarboxylic acids | HOFFMANN-LA ROCHE INC. (US) | 1985-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256161-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | FGB, F13B, F2 | PPARG 1067/4885PPARD 948/4885PPARA 1496/4885 |
| US-20070021489-A1 | Fibrinogen receptor antagonists and their use | FGB, F13B, F2 | PPARG 1067/4885PPARD 948/4885PPARA 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.