Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.57 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9498908 | 0.99 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL2015635 | 0.87 | PPARG (0.63) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| Hydrochloric Acid SCHEMBL9545982 | 0.85 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL9194187 | 0.85 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL5804482 | 0.83 | PPARG (0.58) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL9157243 | 0.83 | CYSLTR2 (0.80) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL9192587 | 0.82 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL10685393 | 0.81 | PPARG (0.78) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL11279092 | 0.80 | PPARG (0.69) | CYSLTR2CYSLTR1LMNAPPARGPPARD | |
| SCHEMBL9383779 | 0.79 | CYSLTR2 (0.67) | CYSLTR2CYSLTR1LMNAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | disclosed |
| US-5167949-A | Antiallergic | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-12-01 | — | — | US | disclosed |