Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30280749 | 0.89 | TTR (0.37) | CDK1CCNB1GAAHPGD | |
| SCHEMBL12488293 | 0.89 | TTR (0.37) | CDK1CCNB1GAAHPGD | |
| SCHEMBL18432284 | 0.82 | ALDH1A1 (0.37) | ALDH1A1POLBGAASMN1; SMN2HPGD | |
| SCHEMBL28224 | 0.69 | TSHR (0.58) | TSHRALDH1A1HTTMAPTPOLB | |
| SCHEMBL17244908 | 0.68 | TSHR (0.51) | TSHRALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19113109 | 0.67 | BRS3 (0.32) | — | |
| SCHEMBL20156410 | 0.67 | FASN (0.39) | — | |
| SCHEMBL28713805 | 0.67 | PTGS1 (0.45) | TSHRALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL29981018 | 0.66 | DHODH (0.36) | SMN1; SMN2 | |
| SCHEMBL12489130 | 0.65 | FASN (0.38) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089904-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES, INC. (US) | 2018-05-17 | — | — | WO | disclosed |