Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27420286 | 0.91 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1ATMTP53 | |
| SCHEMBL2623164 | 0.86 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL13160759 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL26290552 | 0.85 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL12026823 | 0.83 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL20156716 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TDP1ATMTP53 | |
| SCHEMBL9957587 | 0.82 | CYP4F2 (0.45) | SMN1; SMN2ALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL18904538 | 0.82 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1TDP1TP53CYP3A4 | |
| SCHEMBL13449843 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL15984467 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1TDP1ATMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086556-A1 | POLYMER AND DEVICE FOR CAPTURING OR SEPARATING LEUCOCYTES, MANUFACTURING METHOD AND USE THEREOF | 普瑞博生技股份有限公司 | 2018-05-17 | — | — | WO | disclosed |