SCHEMBL20156716

SCHEMBL20156716

CCCCOC(=O)C(C)(C)CC(C)C(=O)OCC1CO1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
ALDH1A1 P00352 5/20 0.37
TDP1 Q9NUW8 1/20 0.37
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ATM Q13315 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
ENPP2 Q13822 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14516867 0.82 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL20156745 0.82 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL15984467 0.81 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL12756289 0.81 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL21135286 0.79 ALDH1A1 (0.35) ALDH1A1TP53CYP3A4
SCHEMBL13941998 0.77 ALDH1A1 (0.46) ALDH1A1TP53CYP3A4TSHRMAPK1
SCHEMBL27420286 0.77 SMN1; SMN2 (0.42) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL12026823 0.75 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL9925444 0.74 CA1 (0.48) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4
SCHEMBL26312422 0.74 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1TDP1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833289-B2 Polymer and device for capturing or separating leucocytes, manufacturing method and use thereof Puriblood Medical Co., Ltd. (TW) 2023-12-05 US disclosed
EP-3539581-A1 POLYMER AND DEVICE FOR CAPTURING OR SEPARATING LEUCOCYTES, MANUFACTURING METHOD AND USE THEREOF Puriblood Medical Co., Ltd. (TW) 2019-09-18 EP disclosed
WO-2018086556-A1 POLYMER AND DEVICE FOR CAPTURING OR SEPARATING LEUCOCYTES, MANUFACTURING METHOD AND USE THEREOF 普瑞博生技股份有限公司 2018-05-17 WO disclosed