Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077499 | 0.81 | P2RX7 (0.32) | P2RX7TNFRIPK1 | |
| SCHEMBL21725759 | 0.77 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL2535144 | 0.77 | P2RX7 (0.40) | NR3C1PGRNR3C2ARP2RX7 | |
| SCHEMBL18876075 | 0.76 | NR3C1 (0.44) | NR3C1PGRNR3C2ARP2RX7 | |
| SCHEMBL12278916 | 0.74 | TNF (0.36) | P2RX7EIF4A3TNFRIPK1 | |
| SCHEMBL18999654 | 0.72 | CCR8 (0.33) | P2RX7KMT2A | |
| SCHEMBL5495898 | 0.72 | AHR (0.35) | NR3C1PGRNR3C2ARP2RX7 | |
| SCHEMBL23685895 | 0.70 | AHR (0.42) | NR3C1PGREIF4A3TNFRIPK1 | |
| SCHEMBL20356540 | 0.70 | NR3C1 (0.33) | NR3C1PGRNR3C2ARP2RX7 | |
| SCHEMBL22095933 | 0.69 | HTR1D (0.35) | P2RX7TNFRIPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |