Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157346 | 0.84 | HTT (0.38) | KDM4EALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL20156901 | 0.81 | HTT (0.41) | KDM4EALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL20156905 | 0.77 | HTT (0.42) | KDM4EALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL20157328 | 0.76 | HTT (0.40) | KDM4EALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL20157036 | 0.74 | HTT (0.43) | KDM4EALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL20157029 | 0.72 | ALDH1A1 (0.40) | KDM4EALDH1A1HTTTSHRSMN1; SMN2 | |
| SCHEMBL20157027 | 0.69 | HTT (0.38) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL20157210 | 0.69 | KDM4E (0.43) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL20157025 | 0.68 | MEN1 (0.34) | KDM4EALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL20140044 | 0.66 | MTOR (0.54) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |