Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156902 | 0.80 | ALDH1A1 (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20157195 | 0.75 | GRIN2B (0.39) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20157027 | 0.74 | HTT (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL20157044 | 0.71 | GRIN2B (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20157045 | 0.69 | GRIN2B (0.34) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20156905 | 0.69 | HTT (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL20157312 | 0.68 | GRIN2B (0.33) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL20157210 | 0.68 | KDM4E (0.43) | MEN1KMT2AALDH1A1HRH3HTT | |
| SCHEMBL20157036 | 0.68 | HTT (0.43) | MEN1KMT2ASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL20156899 | 0.68 | KDM4E (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |