Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.41 |
| ▸ | DNM2 | P50570 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528975 | 0.79 | EPHX1 (0.39) | GPR84DNM2ADRA2ACISD1 | |
| SCHEMBL11023376 | 0.74 | CYP3A4 (0.40) | GPR84DNM2ADRA2ACISD1 | |
| SCHEMBL12959658 | 0.74 | PRSS1 (0.41) | GPR84DNM2CISD1 | |
| SCHEMBL5284421 | 0.74 | GUCY1A1 (0.54) | — | |
| SCHEMBL11329911 | 0.74 | PLK1 (0.47) | — | |
| SCHEMBL11329867 | 0.74 | PLK1 (0.47) | — | |
| SCHEMBL11337228 | 0.74 | PLK1 (0.47) | — | |
| SCHEMBL11331968 | 0.74 | PLK1 (0.47) | — | |
| SCHEMBL11335028 | 0.74 | PLK1 (0.47) | — | |
| SCHEMBL11338770 | 0.74 | PLK1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |