SCHEMBL7528975

SCHEMBL7528975

CCCCCCCCCCCCNc1cc(C)c(C=O)cc1C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH4 P08319 1/20 0.39
ADH7 P40394 1/20 0.39
GPR84 Q9NQS5 9/20 0.38
DNM2 P50570 1/20 0.35
ADRA2A P08913 1/20 0.35
CISD1 Q9NZ45 5/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20157002 0.79 GPR84 (0.41) GPR84DNM2ADRA2ACISD1
SCHEMBL8979424 0.77 ABL1 (0.49) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL21367256 0.75 ALDH1A1 (0.47) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL28035949 0.74 L3MBTL1 (0.48) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL7285847 0.72 L3MBTL1 (0.46) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL9104213 0.72 L3MBTL1 (0.43) EPHX1ADH1BADH1CADH1AADH4
SCHEMBL11335028 0.70 PLK1 (0.47)
SCHEMBL11331968 0.70 PLK1 (0.47)
SCHEMBL11337228 0.70 PLK1 (0.47)
SCHEMBL11329867 0.70 PLK1 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684517-B1 Photographic element with silver halide emulsion layer of low developability and having an associated high dye-yield coupler EASTMAN KODAK CO (US) 2002-07-24 EP disclosed
EP-0684514-B1 Tight-wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK CO (US) 2002-07-17 EP disclosed
EP-0684516-B1 Photographic element containing a high dye-yield coupler with a methine dye chromophore EASTMAN KODAK CO (US) 2002-01-23 EP disclosed
EP-0684518-B1 Photographic element containing high dye-yield couplers having improved reactivity EASTMAN KODAK CO (US) 2001-07-18 EP disclosed
US-6007973-A Tight wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK COMPANY (US) 1999-12-28 US disclosed
US-5998121-A HIGH DYE-YIELD COUPLER THAT RELEASES A DYE OR DYE PRECURSOR HAVING AN ELECTRICALLY NEUTRAL DYE CHROMOPHORE. EASTMAN KODAK COMPANY (US) 1999-12-07 US disclosed
EP-0684514-A1 Tight-wrapped photographic element containing a high dye-yield coupler EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684516-A1 Photographic element containing a high dye-yield coupler with a methine dye chromophore EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684517-A1 Photographic element with silver halide emulsion layer of low developability and having an associated high dye-yield coupler EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
EP-0684518-A1 Photographic element containing high dye-yield couplers having improved reactivity EASTMAN KODAK COMPANY (US) 1995-11-29 EP disclosed
US-5470688-A Heat development of elements containing methine-dye releasing couplers EASTMAN KODAK COMPANY (US) 1995-11-28 US disclosed
US-5457004-A Exposure the element, comprising a substrate and a photographic silver halide emulsion layer associated with high yield coupler, with oxidized color developer forming an image EASTMAN KODAK COMPANY (US) 1995-10-10 US disclosed
US-5455140-A Image quality, preferred hues EASTMAN KODAK COMPANY (US) 1995-10-03 US disclosed
US-5447819-A Photographic element containing high dye-yield couplers having improved reactivity EASTMAN KODAK COMPANY (US) 1995-09-05 US disclosed