Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20139947 | 0.98 | HTR2C (0.42) | HTR2CCCR1CCR8OPRM1OPRL1 | |
| SCHEMBL171375 | 0.90 | DRD2 (0.44) | — | |
| SCHEMBL12093290 | 0.89 | HTR2C (0.47) | HTR2CCCR1CCR8OPRM1OPRL1 | |
| SCHEMBL30469416 | 0.89 | HTR2C (0.47) | HTR2CCCR1CCR8OPRM1OPRL1 | |
| SCHEMBL30599933 | 0.85 | CCR1 (0.46) | CCR1CCR8OPRM1OPRL1 | |
| SCHEMBL1742160 | 0.85 | CCR1 (0.46) | CCR1CCR8OPRM1OPRL1 | |
| SCHEMBL14869055 | 0.79 | MPO (0.41) | OPRM1OPRL1HTR3A | |
| SCHEMBL14868947 | 0.79 | PARP1 (0.41) | HTR3A | |
| SCHEMBL1610517 | 0.79 | CCR1 (0.52) | CCR1CCR8OPRM1OPRL1 | |
| SCHEMBL30472085 | 0.79 | CHRNA7 (0.39) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |