Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | FASN | P49327 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157195 | 0.84 | GRIN2B (0.39) | PLA2G1BPOLBATG4BGRIN2BMEN1 | |
| SCHEMBL20157205 | 0.80 | MTOR (0.54) | MTORRPTORMLST8GRIN2BMEN1 | |
| SCHEMBL20157044 | 0.77 | GRIN2B (0.35) | PLA2G1BPOLBATG4BGRIN2BMEN1 | |
| SCHEMBL20157045 | 0.76 | GRIN2B (0.34) | PLA2G1BPOLBATG4BGRIN2BMEN1 | |
| SCHEMBL20157312 | 0.75 | GRIN2B (0.33) | PLA2G1BPOLBATG4BGRIN2BMEN1 | |
| SCHEMBL20157222 | 0.72 | GRIN2B (0.38) | GRIN2BMEN1KMT2A | |
| SCHEMBL20157118 | 0.71 | MTOR (0.76) | MTORRPTORMLST8FASN | |
| SCHEMBL20157290 | 0.69 | MTOR (0.50) | MTORRPTORMLST8MEN1KMT2A | |
| SCHEMBL20157298 | 0.65 | PLA2G1B (0.38) | PLA2G1BPOLBATG4BGRIN2BMEN1 | |
| SCHEMBL20157307 | 0.65 | PLA2G1B (0.38) | PLA2G1BPOLBATG4BGRIN2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |