Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.50 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157205 | 0.88 | MTOR (0.54) | MTORRPTORMLST8ALDH1A1NPSR1 | |
| SCHEMBL20141098 | 0.84 | MTOR (0.71) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20156911 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1NPSR1DRD2DRD4 | |
| SCHEMBL20157212 | 0.77 | GBA1 (0.51) | KDM4EALDH1A1NPSR1DRD2DRD4 | |
| SCHEMBL20140044 | 0.73 | MTOR (0.54) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20157118 | 0.73 | MTOR (0.76) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20140693 | 0.71 | HCRTR1 (0.49) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20157066 | 0.70 | MTOR (0.46) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20156931 | 0.70 | MTOR (0.51) | MTORRPTORMLST8KDM4EALDH1A1 | |
| SCHEMBL20157082 | 0.70 | MYC (0.54) | KDM4EALDH1A1NPSR1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |