Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FABP6 | P51161 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157045 | 0.93 | GRIN2B (0.34) | GRIN2BPLA2G1BPOLBATG4BALDH1A1 | |
| SCHEMBL20157195 | 0.92 | GRIN2B (0.39) | GRIN2BPLA2G1BPOLBATG4BALDH1A1 | |
| SCHEMBL20157312 | 0.84 | GRIN2B (0.33) | GRIN2BPLA2G1BPOLBATG4BALDH1A1 | |
| SCHEMBL20157222 | 0.79 | GRIN2B (0.38) | GRIN2BALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL20157206 | 0.77 | MTOR (0.40) | GRIN2BPLA2G1BPOLBATG4BMEN1 | |
| SCHEMBL20156902 | 0.72 | ALDH1A1 (0.35) | POLBALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL20157307 | 0.71 | PLA2G1B (0.38) | GRIN2BPLA2G1BPOLBATG4BALDH1A1 | |
| SCHEMBL20157298 | 0.71 | PLA2G1B (0.38) | GRIN2BPLA2G1BPOLBATG4BALDH1A1 | |
| SCHEMBL20157025 | 0.71 | MEN1 (0.34) | POLBALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL20157000 | 0.70 | MEN1 (0.41) | GRIN2BPLA2G1BPOLBATG4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |