Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30850018 | 0.78 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL22345803 | 0.78 | KEAP1 (0.42) | KEAP1NFE2L2 | |
| SCHEMBL14554115 | 0.76 | KEAP1 (0.44) | KEAP1NFE2L2 | |
| SCHEMBL29260193 | 0.75 | KEAP1 (0.56) | KEAP1NFE2L2 | |
| SCHEMBL6222738 | 0.64 | KEAP1 (0.50) | KEAP1NFE2L2 | |
| SCHEMBL3939862 | 0.62 | CYP1A2 (0.48) | KEAP1NFE2L2 | |
| SCHEMBL26961127 | 0.62 | KEAP1 (0.43) | KEAP1NFE2L2 | |
| SCHEMBL24586494 | 0.62 | KEAP1 (0.33) | KEAP1NFE2L2 | |
| SCHEMBL26136947 | 0.62 | KEAP1 (0.36) | KEAP1NFE2L2 | |
| SCHEMBL23694779 | 0.61 | CYP1A2 (0.40) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |