Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3939862 | 0.77 | CYP1A2 (0.48) | KEAP1NFE2L2 | |
| SCHEMBL29260193 | 0.77 | KEAP1 (0.56) | KEAP1NFE2L2 | |
| SCHEMBL20157240 | 0.76 | KEAP1 (0.38) | KEAP1NFE2L2 | |
| SCHEMBL6222738 | 0.70 | KEAP1 (0.50) | KEAP1NFE2L2 | |
| SCHEMBL18603197 | 0.70 | AGBL2 (0.30) | — | |
| SCHEMBL21148298 | 0.67 | PDE3B (0.40) | — | |
| SCHEMBL8235252 | 0.67 | KEAP1 (0.47) | KEAP1NFE2L2 | |
| SCHEMBL8237996 | 0.67 | KEAP1 (0.47) | KEAP1NFE2L2 | |
| SCHEMBL21597018 | 0.67 | KEAP1 (0.52) | KEAP1NFE2L2 | |
| SCHEMBL7526744 | 0.67 | KEAP1 (0.47) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013004785-A1 | HETEROARYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF AS SOLUBLE GUANYLATE CYCLASE STIMULATORS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-10 | — | — | WO | disclosed |