Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140687 | 1.00 | KDM5A (0.53) | KDM5ATRPV3HTR1ADRD2DRD4 | |
| SCHEMBL20140593 | 0.93 | HTR1A (0.54) | TRPV3HTR1ADRD2DRD4GRM5 | |
| SCHEMBL3001502 | 0.90 | GRM5 (0.48) | KDM5AHTR1ADRD2DRD4GRM5 | |
| SCHEMBL31232914 | 0.90 | GRM5 (0.48) | KDM5AHTR1ADRD2DRD4GRM5 | |
| SCHEMBL30912532 | 0.87 | TRPV3 (0.52) | TRPV3HPGDSPDE4BGPR119USP30 | |
| SCHEMBL31383577 | 0.87 | TRPV3 (0.52) | TRPV3HPGDSPDE4BGPR119USP30 | |
| SCHEMBL30912414 | 0.87 | TRPV3 (0.52) | TRPV3HPGDSPDE4BGPR119USP30 | |
| SCHEMBL23554565 | 0.85 | TRPV3 (0.53) | TRPV3HPGDSPDE4BGPR119USP30 | |
| SCHEMBL28769777 | 0.83 | TRPV3 (0.46) | TRPV3HPGDSPDE4BGPR119USP30 | |
| SCHEMBL30374041 | 0.82 | GRM5 (0.45) | KDM5AHTR1ADRD2DRD4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |