Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 7/20 | 0.39 |
| ▸ | DRD4 | P21917 | 7/20 | 0.39 |
| ▸ | DRD3 | P35462 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921222 | 0.82 | ALDH1A1 (0.44) | HRH3KDM4EALDH1A1GAAMAPT | |
| SCHEMBL8852051 | 0.80 | KCNH2 (0.47) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL19222360 | 0.79 | KCNH2 (0.50) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL20180121 | 0.79 | KCNH2 (0.50) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL18626629 | 0.79 | KCNH2 (0.50) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL991122 | 0.78 | CCR1 (0.46) | HRH3KDM4EALDH1A1GAAMAPT | |
| SCHEMBL19865657 | 0.75 | CHRM2 (0.46) | HRH4HRH3KDM4EALDH1A1GAA | |
| SCHEMBL18682734 | 0.75 | CCR1 (0.52) | HRH3KDM4EMAPTPDE10ATAS1R3 | |
| SCHEMBL8665678 | 0.73 | CCR1 (0.41) | KDM4EALDH1A1MAPTPDE10ATAS1R3 | |
| SCHEMBL20099862 | 0.72 | PDE10A (0.42) | KDM4EALDH1A1MAPTPDE10ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |