SCHEMBL20157413

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20157811	0.88	SRD5A2 (0.36)	UCHL1MAPTHTTGAASMN1; SMN2
	SCHEMBL20157630	0.87	CNR2 (0.36)	UCHL1NPC1MAPTGAARAB9A
	SCHEMBL20157420	0.87	CXCR2 (0.36)	UCHL1MAPTGAASMN1; SMN2TP53
	SCHEMBL20157482	0.86	UCHL1 (0.38)	UCHL1NPC1MAPTGAASMN1; SMN2
	SCHEMBL21352020	0.85	UCHL1 (0.35)	UCHL1ACHE
	SCHEMBL21352023	0.85	ACHE (0.41)	UCHL1MAPTHTTRAB9AMAPK1
	SCHEMBL20157941	0.84	CA1 (0.33)	UCHL1CA2
	SCHEMBL20157615	0.83	UCHL1 (0.48)	UCHL1NPC1MAPTHTTGAA
	SCHEMBL21354509	0.82	UCHL1 (0.39)	UCHL1MAPTHTTGAANPSR1
	SCHEMBL20157423	0.80	SRD5A2 (0.36)	UCHL1MAPTHTTGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.